天职药房 MISSION (HOUGANG) MEDICAL CLINIC

Fasenra: What is it and What you need to Know

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Welcome to an in-depth exploration of Fasenra! This wonder drug, also known by its active substance benralizumab, offers a new lease on life for severe eosinophilic asthma patients. But what is Fasenra exactly? You’ll find it’s much more than a complex name. As we delve into the details, you’ll understand its significance and how it works.

But we won’t stop there. It’s crucial to grasp not only the functionality of Fasenra but also how to safely administer and store it. A well-informed patient is a step towards successful treatment. Let’s embark on this journey towards a better understanding of Fasenra together.

As always, please consult a medical professional for more information.

What is Fasenra and What is it Used For?

Fasenra (benralizumab)

Fasenra, with its active substance benralizumab, is an additional treatment for severe eosinophilic asthma in patients aged 12 and older. This medical condition, characterized by high levels of eosinophils – a type of white blood cell, heavily contributes to inflammation in asthma.

Fasenra works by directly targeting and eliminating these eosinophils, which effectively reduces associated inflammation. Here’s how it works:

  1. Recognizes and binds to the interleukin-5 receptor (IL-5Rα) on the surface of eosinophils and basophils
  2. Attracts natural killer cells to induce rapid apoptosis (cell death)

Understanding how Fasenra functions is crucial in learning about its administration process and potential side effects — topics we’ll discuss next.

How to Take/Use Fasenra Safely and Effectively

Administering Fasenra correctly is crucial for both its safety and effectiveness. Patients have two primary methods for receiving this medication:

1. Pre-filled Syringe

  • Sanitize hands thoroughly before handling the syringe.
  • Inspect the syringe for any discoloration or particulate matter; do not use if the liquid looks cloudy or contains visible particles.
  • Administer the injection into the upper arm, thigh, or abdomen, avoiding areas where the skin is tender, bruised, red, or hard.
  • Follow your healthcare provider’s instructions regarding injection technique and rotation of injection sites.

2. Autoinjector Pen

  • Start by washing hands and inspecting the pen, ensuring the solution is clear and free of particles.
  • Remove the cap from the autoinjector pen to reveal the needle.
  • Place the autoinjector pen against the injection site—similarly to the syringe locations—and press down until a click is heard.
  • Hold in place for the duration indicated by your healthcare provider to ensure full dosage delivery.

Patients should receive proper training from a healthcare professional on the injection process and administration techniques before attempting self-injection. Accurate administration not only optimizes treatment outcomes but also minimizes potential risks associated with improper usage.

Can I buy the medication over the counter?

No, Fasenra (benralizumab) cannot be bought over the counter. It is a prescription medication and must be prescribed by a healthcare provider. As Fasenra is administered by injection, it is typically done in a clinical setting. Thus it requires a healthcare professional to determine if it is appropriate for a patient’s condition and to monitor its use.

Always consult with a healthcare provider for proper diagnosis and treatment options.

What to Do If You Miss a Dose?

Staying on track with the Fasenra dosing schedule is crucial for managing severe eosinophilic asthma effectively. However, life happens, and doses can be missed. Should you realize you’ve skipped a dose, missed dose precautions come into play:

  • Act Promptly: If the missed dose is noticed within three days of the scheduled date, administer the injection as soon as possible.
  • Resume Schedule: After the missed dose is taken, continue with the next dose at its regularly scheduled time.
  • Avoid Doubling Up: Never take a double dose to make up for the one that was missed.
  • Seek Advice: Consult your healthcare provider for guidance specific to your treatment plan if the delay in dosing is more than three days.

Remembering these steps ensures continuity in your treatment and maintains Fasenra’s effectiveness in controlling your asthma symptoms.

Precautions and Warnings When Using Fasenra

When using Fasenra, it’s important to keep the following precautions in mind:

  • Potential for Allergic Reactions and Hypersensitivity: If you’ve had a drug allergy before, Fasenra may not be suitable for you. Seek immediate medical attention if you experience any signs of an allergic reaction, such as hives, difficulty breathing, or swelling of your face, lips, tongue, or throat.

  • Consultation with a Healthcare Professional: Before starting Fasenra treatment, it’s crucial to consult with a healthcare professional who can provide personalized advice based on your medical history.

  • Special Attention for Patients with Hepatic or Renal Impairment: While no specific dosage adjustments have been recommended for patients with liver or kidney problems, it’s important to exercise caution. Always inform your healthcare provider about any existing conditions to ensure safe use.

Take note, prioritizing safety is key when it comes to managing your health. Stay informed and take the necessary precautions when using medications like Fasenra.

What are the Side Effects of Fasenra?

Before you start taking Fasenra, it’s important to know about the possible side effects. In most cases, they are mild and can be managed. Two of the most common side effects are headache and sore throat.

While these may not seem like major issues, they can still have an impact on your daily life. If you frequently experience either of these side effects, it’s a good idea to talk to your doctor. They can provide advice on how to deal with them or explore other treatment options besides Fasenra.

It’s worth noting that everyone’s experience with Fasenra may be different. Some people may have these side effects, while others may not. That’s why it’s crucial to pay attention to your health and promptly inform your doctor about any changes you notice.

What are the Potential Rare but Serious Side Effects of Fasenra?

While Fasenra is effective for many, it’s crucial to be aware of potential serious side effects that could occur, albeit rarely. Two of the most critical concerns are allergic reactions and anaphylaxis. These can manifest as:

  • Hives or rash
  • Difficulty breathing
  • Swelling of the face, lips, tongue, or throat
  • A feeling of warmth
  • Severe dizziness or fainting

If you experience any such symptoms, it is vital to seek immediate medical attention as these conditions can be life-threatening. Quick recognition and response can make a significant difference in the outcomes of such serious adverse events. Always carry information about your Fasenra prescription with you to inform healthcare providers promptly in case of emergencies.

Managing Food and Medication Interactions with Fasenra

When taking Fasenra, it’s essential to be aware of possible interactions with other substances. Here’s what you need to know:

Fasenra and Food

Currently, there are no specific foods that you must avoid while on Fasenra. However, maintaining a balanced diet is crucial for overall health and managing asthma.

Fasenra and Other Medications

While no significant medication interactions have been reported, always inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and supplements.

To avoid potential interactions:

  1. Provide a complete list of your medications to your healthcare professional.
  2. Check with your pharmacist when adding new medications.
  3. Follow the provided medication usage instructions precisely.

By staying informed and vigilant about what you ingest alongside Fasenra, you can help ensure your treatment remains safe and effective.

Proper Storage and Disposal of Fasenra

Attending to medication storage is paramount when handling Fasenra. Keep it in the original package, protect it from light, and store it in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze or shake the pre-filled syringe or autoinjector pen.

When it comes to unused or expired Fasenra, proper medication disposal is crucial. Don’t toss it into household waste or flush it down the toilet. Instead, consult with your healthcare provider or local pharmacy for guidance on safe disposal methods.

Read More: Apalutamide: What is it and What you need to Know

Picture of MMC Writing Team

MMC Writing Team

An Apple a day keeps the doctor away. We hope that we can provide you with information to stay healthy.

Picture of MMC Writing Team

MMC Writing Team

An Apple a day keeps the doctor away. We hope that we can provide you with information to stay healthy.

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